8 International Workshop on Chemical Exchange Saturation Transfer Imaging

CEST 2020

Click here to download the program

The Announcement about the CEST MRI Webinar

Sept 24th

Due to continuing safety concerns and public health restrictions with respect to gatherings during the COVID-19 pandemic, the international workshop on chemical exchange saturation transfer imaging has been transitioned into a virtual conference in 2020, followed by an in person meeting in 2021 (CEST2021).

CESTers

University of Torino

Silvio Aime, Ph.D.

Linda Knutsson, Ph.D.

Lund University, Sweden

German Cancer Research Center

Daniel Paech, MD.

Mark D Pagel, Ph.D.

MD Anderson Cancer Center

University of Pennsylvania

Ravinder Reddy, Ph.D.

Dean Sherry, Ph.D.

University of Texas, Southwestern

Vanderbilt University

Seth Smith, Ph.D.

Phillip Zhe Sun, Ph.D.

Emory University

Johns Hopkins University

Peter van ZiJl, Ph.D.

Moriel Vandsburger, Ph.D.

University of California, Berkeley

Moritz Zaiss, Ph.D.

Max Planck Institutes, Germany

Jinyuan Zhou, Ph.D.

Johns Hopkins University

Introduction to CEST for MRI Assessment of Brain Ischemia and Cancer Lesions

Registration

Program (follows Eastern Standard Time)

Click here to download the E-poster program

Day 1 - Monday, 9 November 2020

09:00~09:50

E-poster Session 1

09:50~10:00

Welcome

Phillip Zhe Sun, Ph.D., Emory University, Atlanta, GA, USA

10:00~11:00

Session 1: Contrast Agents and Sequences

Moderators: Dario Longo, Ph.D., Dean Sherry, Ph.D., Xiang Xu, Ph.D.

10:00~

Label-free CEST MRI reveals improved drug delivery of metformin to pancreatic tumors using iRGD-decorated liposomes, Zelong Chen, Southern Hospital, Guangzhou, China

10:07~

Protein Optimization Evolving Tool (POET) based on Genetic Programming

Alexander Bricco, Michigan State University, East Lansing, MI, USA

10:14~

The intramolecular catalysis of the proton exchange process affects the CEST properties of an hydroxycontaining Eu(III) paramagnetic complex, Simona Baroni, University of Torino, Torino, Italy

10:21~

Relayed nuclear Overhauser enhancement (rNOE) imaging with magnetization transfer contrast (MTC) suppression at 3 Tesla, Jianpan Huang, City University of Hong Kong, Hong Kong, China

10:28~

The effect of B1 and Magnetization transfer (MT) on the removed Variable Delay Multi-Pulse Chemical Exchange Saturation Transfer (VDMP-CEST) imaging of the human brain at 7T, Bárbara Schmitz-Abecassis, Leiden University Medical Center, Leidenm Netherlands

10:35~

Concatenate multislice CEST imaging using unevenly segmented RF irradiation - application to NHP brain, Hahnsung Kim, Emory University, Atlanta, GA, USA

10:42~

Q & A

11:00~11:10

Break

11:10~11:20

Philips - 3D Amide Proton Transfer: Product & next steps towards clinical adoption

Kim van de Ven, Ph.D

11:20~12:20

Session 2: Tumor

Moderators: Jinyuan Zhou, Ph.D., Daniel Paech, MD., Kannie Chan, Ph.D.

11:20~

IDH-mutant 1p/19q retained gliomas with T2-FLAIR mismatch selectively identified by fluid suppression in APTw imaging, Stefano Casagranda, Olea Medical, La Ciotat, France

11:27~

Optimized acquisition protocol for routine clinical APT and rNOE CEST-MRI at 3T

Steffen Goerke, German Cancer Research Center (DKFZ), Heidelberg, Germany

11:34~

An Hybrid denoising method for improving CEST-MRI contrast quantification

Feriel Romdhane, University of Torino, Torino, Italy

11:41~

Assessment of early response to neoadjuvant systemic therapy (NAST) of triple-negative breast cancer (TNBC), Shu Zhang, MD Anderson Cancer Center, Houston, TX, USA

11:48~

Multislice RARE based single-shot CEST MRI for volumetric tumor acidosis characterization

Daisy Villano, University of Torino, Torino, Italy

11:55~

Concentration-independent mapping of absolute pH values in vivo using amide and guanidyl CEST-MRI at 9.4 T, Philip Boyd, German Cancer Research Center (DKFZ), Heidelberg, Germany

12:02~

Q & A

12:20~13:20

E-poster Session 1

Day 2 - Tuesday, 10 November 2020

09:00~10:00

E-poster Session 2

10:00~11:00

Session 3: Data Analysis and Machine Learning

Moderators: Moritz Zaiss, Ph.D., Elena Vinogradov, Ph.D., Jiadi Xu, Ph.D.

10:00~

Deep CEST MR fingerprinting reveals tumor apoptotic response to oncolytic virotherapy in vivo

Or Perlman, Massachusetts General Hospital, Charlestown, MA, USA

10:07~

Deep learning with uncertainty quantification for acceleration of 7T CEST acquisition and reconstruction, Kiril Klein, University Erlangen-Nuremberg, Erlangen, Germany

10:14~

Automated multi-pool CEST/MT optimal experiment design and deep quantitative mapping (AutoCEST), Or Perlman, Massachusetts General Hospital, Charlestown, MA, USA

10:21~

High-resolution phosphocreatine mapping using artificial neural network-based CEST MRI at 3T: A validation study, Lin Chen, Johns Hopkins University, Baltimore, MD, USA

10:28~

Machine learning-based classification of breast cancer cell types in a preclinical model using CEST MRI, Chongxue Bie, Northwest University, Xi'an, China

10:35~

Linear projection-based 7T CEST reconstruction

Moritz Fabian, University Hospital Erlangen, Erlangen, Germany

10:42~

Q & A

11:00~11:10

Break

11:10~11:20

Siemens - It's all about collaboration

Patrick Liebig, Ph.D

11:20~12:20

Session 4: Stroke and Neurology

Moderators: Kristin O'Grady, Ph.D., Ravinder Reddy, Ph.D., Iris Zhou, Ph.D.

11:20~

CEST MRI of disease-associated lymph nodes in a mouse model of multiple sclerosis

Aline Thomas, Johns Hopkins University, Baltimore, MD, USA

11:27~

Investigation of optimizing chemical exchange saturation transfer imaging for epilepsy secondary to tuberous sclerosis complex at 3 Tesla, Qingqing Wen, Zhejiang University, Hangzhou, China

11:34~

Altered D-glucose in brain parenchyma and cerebrospinal fluid of early Alzheimer’s disease detected by dynamic glucose enhanced MRI, Jianpan Huang, City University of Hong Kong, Hong Kong, China

11:41~

Using glutamate-weighted MR imaging (GluCEST) to detect effects of transcranial magnetic stimulation, Abigail Cember, University of Pennsylvania, Philadelphia, PA, USA

11:48~

Comparing common amide proton transfer quantification methods for ischemic stroke detection

Foo Lee Sze, Universiti Tunku Abdul Rahman, Selangor, Malaysia

11:55~

Correction of T1 relaxation change reveals the dominant amide proton transfer MRI signal during acute stroke, Limin Wu, Massachusetts General Hospital, Charlestown, MA, USA

12:02~

Q & A

12:20~13:20

E-poster Session 2

Day 3 - Wednesday, 11 November 2020

09:00~10:00

E-poster Session 3

10:00~11:00

Session 5: Data Processing and Standardization

Moderators: Mark D Pagel, Ph.D., Linda Knutsson, Ph.D., Hye-Young Heo, Ph.D.

10:00~

Induced Saturation Transfer Recovery Steady State (iSTRESS) for proton exchange rate imaging with MRI, Mehran Shaghaghi, University of Illinois at Chicago, Chicago, IL, USA

10:07~

High-sensitivity CEST mapping using the spatiotemporal correlation enhanced method

Lin Chen, Johns Hopkins University, Baltimore, MD, USA

10:14~

7 tricks for 7T CEST – improving reproducibility of multi-pool evaluation

Katrin Khakzar, University Hospital Erlangen, Erlangen, Germany

10:21~

A digital human head phantom for validation of retrospective motion correction in glucoCEST MRI

Patrick Lehmann, Lund University, Lund, Sweden

10:28~

Development of a standard phantom for Chemical Exchange Saturation Transfer (CEST) MRI

Shu Zhang, MD Anderson Cancer Center, Houston, TX, United States

10:35~

pulseq-CEST: Towards reproducible CEST experiments using an open source sequence definition standard, Kai Herz, Max Planck Institute, Tuebingen, Germany

10:42~

Q & A

11:00~11:10

Break

11:10~11:20

Bruker - Preclinical MR & Innovations in CEST

Kristin Granlund, Ph.D., Jerome Voiron, Ph.D

11:20~12:10

Session 6: MSK and New Applications

Moderators: Moriel Vandsburger, Ph.D., Rachelle Crescenzi, Ph.D., Tao Jin, Ph.D.

11:20~

3D creatine chemical exchange saturation transfer imaging of exercised muscle at 7T and its repeatability, Dushyant Kumar, University of Pennsylvania, Philadelphia, PA, USA

11:27~

Delayed urea differential enhancement CEST (dudeCEST)-MRI with T1 correction for monitoring renal urea handling, Soo Hyun Shin, University of California, Berkeley, Berkeley, CA, USA

11:34~

CEST MRI for the characterization of heterogeneity of renal masses: preliminary study

Elena Vinogradov, University of Texas Southwestern Medical Center, Dallas, TX, USA

11:41~

Z-Spectrum MRI to monitor brown fat

Alessandro Scotti, University of Illinois at Chicago, Chicago, IL, USA

11:48~

Chemical exchange-enhanced observation of 17O MR Spectroscopy and Imaging

Ricardo Martinho, Weizmann Institute of Science, Rehovot, Israel

11:55~

Q & A

12:10~12:20

Closing

Phillip Zhe Sun, Ph.D., Emory University, Atlanta, GA, USA

12:20~13:20

E-poster Session 3

Abstracts

1. All investigators in the field of CEST imaging are eligible to submit an abstract for a poster presentation. Students, post-doctoral fellows, and residents are particularly welcome.

2. All studies describing any aspect of CEST imaging are proper. Any studies of human and animal subjects must have been approved by the relevant local ethics committee.

3. All submissions must be submitted to , using the supplied template. The submissions will start from Jun 1st, 2020 and end at 11:59 PM on Sept 9th, 2020 (EDT).

4. All abstracts will be peer-reviewed by a Scientific Committee. The criteria are scientific novelty/quality, relevance to the workshop’s objectives, and clarity of presentation. Decisions about abstract acceptance will be sent on Oct 19th, 2020.

5. Accepted abstracts will be presented as virtual meeting. Further instruction will be sent with the acceptance notifications to the speaker directly.

6. Submission of an abstract is considered a commitment to present the abstract if it is accepted. Please do not submit an abstract unless you are planning to attend the workshop.